White Blood Cells
A Brief Guide
What Are White Blood Cells?
White blood cells, also known as leukocytes, are an essential part of your body's immune system. They play a crucial role in defending your body against infections and foreign invaders, such as bacteria, viruses, and other pathogens. Unlike red blood cells, which primarily carry oxygen to tissues, white blood cells are key players in your body's defense mechanism.

Why Doctors Order the Test?
A white blood cell count, or WBC count, is a common blood test ordered by doctors to assess your body's immune response and overall health. This test measures the number of white blood cells present in your blood sample. An abnormal WBC count, whether elevated or diminished, can indicate underlying health conditions that require further evaluation and treatment.

When It's Too High: Understanding Elevated White Blood Cell Levels
When your white blood cell count is higher than normal, it is called leukocytosis. Elevated white blood cell levels can be a sign that your body is fighting an infection or experiencing inflammation. Common reasons for leukocytosis include bacterial infections, such as pneumonia or urinary tract infections, as well as inflammatory conditions like rheumatoid arthritis.
In some cases, leukocytosis may also be a response to physical or emotional stress. However, persistent or significantly elevated white blood cell counts may warrant further investigation to rule out more serious underlying conditions, such as leukemia or other blood disorders.

When It's Too Low: Understanding Diminished White Blood Cell Levels
Conversely, a lower than normal white blood cell count is known as leukopenia. Diminished white blood cell levels can weaken your body's ability to fight infections, leaving you more susceptible to illnesses. Leukopenia can be caused by various factors, including viral infections (such as HIV or hepatitis), autoimmune disorders, certain medications (such as chemotherapy drugs), bone marrow disorders, or nutritional deficiencies (such as vitamin B12 or folate deficiency).

When High or Low Levels May Be Normal
It's important to note that in some cases, temporary fluctuations in white blood cell counts can be normal and may not necessarily indicate an underlying health problem. For example:

  • High Levels: After intense physical activity, such as exercise, your body may release more white blood cells into the bloodstream temporarily. Additionally, emotional stress or anxiety can also cause a temporary increase in white blood cell counts.
  • Low Levels: Pregnancy can cause a temporary decrease in white blood cell counts due to hormonal changes. Additionally, certain medications can lower white blood cell levels as a side effect.

In such situations, your doctor will consider other clinical factors and may opt for additional tests or monitoring to determine if further action is necessary.

Causes of Falsely Elevated White Blood Cell Levels
While elevated white blood cell levels are often indicative of an immune response to infection or inflammation, certain factors can cause falsely elevated results, leading to misinterpretation. These factors include:

  • Medications: Some medications, such as corticosteroids, lithium, or epinephrine, can stimulate the production or release of white blood cells into the blood stream, leading to artificially elevated counts.
  • Recent Infections or Vaccinations: A recent infection or vaccination can temporarily increase white blood cell levels as your body mounts an immune response. It's essential to inform your healthcare provider about any recent illnesses or vaccinations before undergoing a white blood cell count test.
  • Stress or Physical Exertion: Emotional stress or intense physical activity can stimulate the release of stress hormones, which may temporarily elevate white blood cell counts.

Understanding your white blood cell levels and the factors that can influence them is crucial for maintaining your overall health and well-being. If you have concerns about your white blood cell count or experience symptoms such as fever, fatigue, or recurrent infections, consult your healthcare provider for further evaluation and guidance.